The drug development process is costly and time-consuming.Repurposing existing approved drugs, an Chopping Board efficient and cost-effective strategy, involves assessing numerous drug-protein pairs to uncover new interactions.While modern in silico methods enhance scalability, an open database for projected drug-target interactions across the enti
Development of modern high-frequency components and circuits is heavily based on full-wave electromagnetic (EM) simulation tools.Some phenomena, although important from the point of view of the system performance, e.g., EM cross-coupling effects, feed radiation in antenna arrays, substrate anisotropy, cannot be adequately accounted for using simple
Accurate census is essential for endangered plant management, yet lack of resources may make complete on-the-ground census difficult to achieve.Accessibility, especially for species in fragile habitats, is an added constraint.We examined the feasibility of using UAV (unmanned aerial vehicle, drone)-based imagery for census of an endangered plant sp
Abstract The aim of this study is to evaluate the Nicaraguan screening program for congenital hypothyroidism in terms of coverage and effectiveness of detection and confirmation of cases with the condition throughout a decade.Thyrotropin was quantified in cord-blood samples RESCUE CREAM by a validated ELISA and a cut-off of 20 mU/l was applied.Cove
Brain arteriovenous malformations (bAVMs) are congenital defects of vasculogenesis, the natural history of which is characterized by a significant morbidity and mortality related to the risk of Shower Caps bleeding.Their management remains challenging, since complete eradication is often difficult.Embolization, surgery, or radiosurgery alone are sa